Chromosomal abnormalities in human retinoblastoma a review
نویسندگان
چکیده
منابع مشابه
A review of retinoblastoma disease
Retinoblastoma is a rare type of eye cancer that usually occurs in early childhood, usually before the age of five. This type of cancer occurs in the retina, the light-sensitive tissue behind the eye that recognizes light and color. It is the most common type of eye cancer in children. One-third of all retinoblastomas are inherited, meaning that mutations in the RB1 gene are present in all cell...
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Chromosomal translocations are a hallmark of lymphoid tumours. Multiple myeloma (MM) is a tumour of the plasma cell, the terminally differentiated B lymphoid cell. In recent years, a large number of chromosomal and genetic abnormalities have been detected in myeloma, the most prominent being chromosome 13q deletions and translocations affecting the immunoglobulin heavy chain (IgH) locus on chro...
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Tumors of the pineal region represent about 0.4-1% of intracranial neoplasms, including those tumors of germ cell origin (primarily germinomas and teratomas, which represent about 80% of pineal malignancies), and those tumors of the pineal parenchyma (pineocytoma and pineoblastoma). Pineocytoma is composed of relatively mature cells of the pineal parenchyma, whereas pineoblastoma represents a m...
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Background and Aims: Retinoblastoma tumors are the most common intraocular malignancy in childhood, leading to death after two years. The Human Adenovirus (HAdV) infection could be critical in the retinoblastoma pathogenesis due to the virus and retinoblastoma 1 interactions. The objective of the current study was to investigate the possible presence of the HAdV genome in the retinoblastoma pat...
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Direct testing of the outcome of human female meiosis demonstrated that up over a half of oocytes from IVF patients of advanced reproductive age are aneuploid, originating comparably from meiosis I and meiosis II errors, with potential probability of aneuploidy rescue in an almost half of oocytes with sequential first and second meiotic errors. One fifth of abnormalities originating from meiosi...
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ژورنال
عنوان ژورنال: Cancer
سال: 1986
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19860801)58:3<663::aid-cncr2820580311>3.0.co;2-g